If you are having problems with the new release, and you have upgraded, rather than done a fresh build, a patch is available.
Running queries based on a pre-defined report with query type "Custom Columns ranked by time" will result in a pink error box being generated with message "java.lang.NullPointerException" and "System Error Please contact technical support".
This affects pre-defined report and custom queries with "Custom Columns ranked by time" [ex: IOS IPS DTM - All Events (Total View)]. There are ~70 of these types of reports. This also only affects users that have upgraded from 4.2(1) to 4.2(2) and NOT users that have installed directly from the 4.2(2) ISO CD.